diff --git a/packages/asset-swapper/src/constants.ts b/packages/asset-swapper/src/constants.ts
index 496a76fe49..3cd262b4c8 100644
--- a/packages/asset-swapper/src/constants.ts
+++ b/packages/asset-swapper/src/constants.ts
@@ -52,6 +52,7 @@ const DEFAULT_SWAP_QUOTER_OPTS: SwapQuoterOpts = {
     rfqt: {
         takerApiKeyWhitelist: [],
         makerAssetOfferings: {},
+        txOriginBlacklist: new Set(),
     },
     tokenAdjacencyGraph: DEFAULT_TOKEN_ADJACENCY_GRAPH,
 };
diff --git a/packages/asset-swapper/src/swap_quoter.ts b/packages/asset-swapper/src/swap_quoter.ts
index a514d78609..692da34b5f 100644
--- a/packages/asset-swapper/src/swap_quoter.ts
+++ b/packages/asset-swapper/src/swap_quoter.ts
@@ -410,6 +410,14 @@ export class SwapQuoter {
         return whitelistedApiKeys.includes(apiKey);
     }
 
+    private _isTxOriginBlacklisted(txOrigin: string | undefined): boolean {
+        if (!txOrigin) {
+            return false;
+        }
+        const blacklistedTxOrigins = this._rfqtOptions ? this._rfqtOptions.txOriginBlacklist : new Set();
+        return blacklistedTxOrigins.has(txOrigin.toLowerCase());
+    }
+
     private _validateRfqtOpts(
         sourceFilters: SourceFilters,
         rfqt: RfqtRequestOpts | undefined,
@@ -438,6 +446,19 @@ export class SwapQuoter {
             return undefined;
         }
 
+        // If the requested tx origin is blacklisted, raise a warning and disable RFQ
+        if (this._isTxOriginBlacklisted(txOrigin)) {
+            if (this._rfqtOptions && this._rfqtOptions.warningLogger) {
+                this._rfqtOptions.warningLogger(
+                    {
+                        txOrigin,
+                    },
+                    'Attempt at using a tx Origin that is blacklisted. Disabling RFQ for the request lifetime.',
+                );
+            }
+            return undefined;
+        }
+
         // Otherwise check other RFQ options
         if (
             intentOnFilling && // The requestor is asking for a firm quote
diff --git a/packages/asset-swapper/src/types.ts b/packages/asset-swapper/src/types.ts
index 306ea4e8dd..2a83b33b33 100644
--- a/packages/asset-swapper/src/types.ts
+++ b/packages/asset-swapper/src/types.ts
@@ -286,6 +286,7 @@ export interface RfqtFirmQuoteValidator {
 export interface SwapQuoterRfqtOpts {
     takerApiKeyWhitelist: string[];
     makerAssetOfferings: RfqtMakerAssetOfferings;
+    txOriginBlacklist: Set<string>;
     altRfqCreds?: {
         altRfqApiKey: string;
         altRfqProfile: string;